Our ingredients Benzoyl Peroxide

Benzoyl peroxide is a common therapy recommended as first line treatment for acne.

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Grade Indication Size of effect Comments
A Acne treatment Strong Reduces comedones, papules and pustules, and is suitable for long term maintenance therapy
What is Benzoyl Peroxide?
How does Benzoyl Peroxide work?
How should it be used?
What are the side-effects of using Benzoyl Peroxide?

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the science of Benzoyl Peroxide

Acne treatment

Benzoyl peroxide has a good track record of safety and effectiveness for the treatment of mild acne. In some cases, effectiveness can be increased if used in combination with antibiotic or retinoid creams.

Benzoyl peroxide is considered as first line treatment for mild acne. Strong evidence from scientific studies show that benzoyl peroxide reduces both inflammatory and non-inflammatory lesions.

Benzoyl peroxide in concentrations of 2.5%, 5% and 10% have been shown to be equally effective however higher concentrations have been linked with more side effects.

Moderate acne responds well to combination therapy with benzoyl peroxide, antibiotics and/or retinoids.

Benzoyl peroxide combined with a topical antibiotic, such as clindamycin, has been shown to be effective in large randomised controlled clinical trials. A clinical trial compared the safety of the combinations clindamycin/benzoyl peroxide and adapalene/benzoyl peroxide in patients with mild-to-moderate acne. Results showed that clindamycin/benzoyl peroxide gel had less side effects.

Benzoyl peroxide and topical azelaic acid have also shown to reduce inflammatory and non-inflammatory lesions compared with placebo, but can cause itching, burning, stinging, and redness of the skin.

There is some evidence of increased effectiveness when benzoyl peroxide is used alongside topical tretinoin (a retinoid). A clinical trial testing tretinoin lotion 0.05%, benzoyl peroxide 5% and 10% was carried out in 250 patients suffering from acne. The results showed that tretinoin applied in the morning and benzoyl peroxide applied at night was the most effective with minimal side effects.